It involved a motorcyclist on Mill Creek Road and Highway 126 near Blue River around 2 p.m.
Investigators say 41-year-old David Edwards from Redmond was driving his motorcycle pulling a trailer and crossed into oncoming traffic on Highway 126.
He allegedly hit 77-year-old Ellen Weaver of Eugene who was driving a Honda Accord. She went to the hospital but has since been released.
Edwards was thrown off his motorcycle. He was wearing a helmet, but was pronounced dead at the scene.
OSP is seeking witnesses who were reportedly at the intersection when the crash occurred but left before they could be interviewed.